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Speaker: Prof. Ivan Huc (Ludwig-Maximilians-Universität München, Munich)

Detail Summary
Date 17 September 2018
Time 15:00

Abstract

Aromatic amide oligomers constitute a distinct and promising class of synthetic foldamers – oligomers that adopt stable folded conformations. Single helical structures are predictable and constitute convenient building blocks to elaborate synthetic, protein-sized folded architectures. They possess a high propensity to assemble into double, triple and quadruple helices, or to form sheet-like structures. Cavities can be designed that enable them to act as artificial receptors and molecular motors. These foldamers also show promise in nucleic acid and protein recognition. This lecture will give an overview of the design principles of these functional molecular architectures and highlight recent developments.

Recent work of Prof. Huc

Angewandte, 2018, 57,7888-7892

Chem. Commun., 2018, 54, 5078-5081

Acc. Chem. Res., 2018, 51, 970-977

Nature Chem., 2018, 10, 511-518

Nature Chem., 2018, 10, 405-412

Venue

Science Park 904,  room D1.113

 

Contact

dr. T.J. (Tiddo) Mooibroek

Faculty of Science

Van 't Hoff Institute for Molecular Sciences

This lecture is sponsored by the John van Geuns Foundation.