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Dr Giulia Giubertoni and Dr Zheng Wei have been selected as fellows of the Dutch national 'Faculty of Impact' programme. It will help them to further develop their entrepreneurial and business skills to grow their start-ups InspectT and ENVISENSE into a successful business. Both companies are based on the results of their research at the Van ‘t Hoff Institute for Molecular Sciences (HIMS).

Faculty of Impact fellows receive substantial funding of up to €200,000 to participate in an intensive two-year coaching programme where they can further develop the skills required to make their start-up companies a success.

Dr Giulia Giubertoni - Optical-DOSY

Measuring and characterising active molecular compounds in nanoparticle mixtures

Photo: HIMS.

Giubertoni is working on transforming Optical-DOSY, a method that she invented together with Prof. Sander Woutersen, into a product to be widely used in industrial and academic R&D. For this, the two researchers started their company InspectT.

Optical-DOSY is a platform technology that simultaneously characterises the size and chemical composition of molecules and particles in solution, simply by adding size sensitivity to optical spectroscopy. Among all the potential applications, optical-DOSY is ideally suited for characterising active compounds in (bio)medical nanoparticles, in particular for measuring the encapsulation fraction. Nanoparticles are indeed increasingly used in healthcare to encapsulate pharmaceuticals, enhancing efficiency and safety.

In 2023, Prof. Woutersen and Giubertoni received the NWO Demonstrator grant, and in 2024, Giubertoni received IXA Proof-of-Concept funding and an NWO take-off grant. While these fundings have enabled the development of the first prototype, the intensive coaching program of the Faculty of Impact will enable Giubertoni to transform herself from an academic scientist into a scientific entrepreneur.

Dr Zheng Wei – ENVISENS

Sustainable enzyme-based household biosensors

Photo: HIMS

Tumour biomarker detection remains a major global healthcare challenge, particularly in the development of high-accuracy, cost-effective biosensors suitable for home use. To address this, the HIMS Biocatalysis research group, led by associate professor Dr Francesco Mutti, has developed a biosensor based on engineered enzymes for the detection of NADPH—a key biomarker in various cancers. This biosensor combines high detection accuracy with low production cost, user-friendly operation, and reusability. Its design offers strong potential for both commercial adoption and positive societal impact, especially in improving access to early cancer diagnostics.

The idea for the biosensor originated during one of the PhD projects of Dr Zheng Wei, in which he collaborated with Dr Yuxin Liu and Prof. Felix Löffler from the Max Planck Institute for Colloids and Interfaces in Potsdam (Germany). Together with Dr Mutti, they founded the start-up company ENVISENS, which will develop and commercialise sustainable, affordable, sensitive, and selective enzyme-based biosensors. A joint patent will be filed in the near future. Zheng Wei is currently a postdoc at Chalmers University of Technology in Göteborg (Sweden). He will return to Amsterdam in July 2026 to run ENVISENS and start his Faculty of Impact fellowship.

See also