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Prof. dr. R. (Ron) Wever

Biocatalysis and Bio-organic Chemistry
Faculty of Science
Van 't Hoff Institute for Molecular Sciences
Photographer: Onbekend

Visiting address
  • Science Park 904
  • Room number: C2.225
Postal address
  • Postbus 94157
    1090 GD Amsterdam
Contact details
  • Publications



    • Wever, R., Renirie, R., & Hollmann, F. (2021). Vanadium Chloroperoxidases as Versatile Biocatalysts. In M. Sutradhar, J. A. L. da Silva, & A. J. L. Pombeiro (Eds.), Vanadium Catalysis (pp. 548-563). (Catalysis Series; No. 41). Royal Society of Chemistry. [details]




    • Wever, R., Krenn, B. E., & Renirie, R. (2018). Marine Vanadium-Dependent Haloperoxidases, Their Isolation, Characterization, and Application. In B. S. Moore (Ed.), Marine Enzymes and Specialized Metabolism (Vol. B, pp. 141-201). (Methods in Enzymology; Vol. 605). Academic Press. [details]
    • Zhang, W., Fernandez-Fueyo, E., Ni, Y., van Schie, M., Gacs, J., Renirie, R., Wever, R., Mutti, F. G., Rother, D., Alcalde, M., & Hollmann, F. (2018). Selective aerobic oxidation reactions using a combination of photocatalytic water oxidation and enzymatic oxyfunctionalizations. Nature Catalysis, 1(1), 55-62. [details]


    • But, A., van der Wijst, E., Le Notre, J., Wever, R., Sanders, J. P. M., Bitter, J. H., & Scott, E. L. (2017). Unusual differences in the reactivity of glutamic and aspartic acid in oxidative decarboxylation reactions. Green Chemistry, 19(21), 5178-5186.
    • Dong, J. J., Fernández-Fueyo, E., Li, J., Guo, Z., Renirie, R., Wever, R., & Hollmann, F. (2017). Halofunctionalization of alkenes by vanadium chloroperoxidase from Curvularia inaequalis. Chemical Communications, 53(46), 6207-6210. [details]
    • Prinsen, P., Narani, A., Hartog, A. F., Wever, R., & Rothenberg, G. (2017). Dissolving Lignin in Water through Enzymatic Sulfation with Aryl Sulfotransferase. ChemSusChem, 10(10), 2267-2273. [details]
    • Wever, R., & Barnett, P. (2017). Vanadium Chloroperoxidases: The Missing Link in the Formation of Chlorinated Compounds and Chloroform in the Terrestrial Environment? Chemistry - An Asian Journal, 12(16), 1997-2007. Advance online publication.
    • Wever, R., Corr, M. J., Goss, R. J. M., & Kamer, P. (2017). Biocatalysis. In P. C. J. Kamer, D. Vogt, & J. W. Thybaut (Eds.), Contemporary Catalysis: Science, Technology and Applications (pp. 249-276). The Royal Society of Chemistry. [details]
    • Wever, R., Goss, R. J. M., Tong, X., & Hartog, A. F. (2017). An Introduction to Biocatalysis. In P. C. J. Kamer, D. Vogt, & J. W. Thybaut (Eds.), Contemporary Catalysis: Science, Technology and Applications (pp. 131-155). The Royal Society of Chemistry. [details]




    • Babich, L., Peralta, J. L. V. M., Hartog, A. F., & Wever, R. (2013). Phosphorylation by alkaline phosphatase: immobilization and synthetic potential. International Journal of Chemistry, 5(3), 87-98. [details]
    • Marhol, P., Hartog, A. F., van der Horst, M. A., Wever, R., Purchartová, K., Fuksova, K., Kuzma, M., Cvačka, J., & Křen, V. (2013). Preparation of silybin and isosilybin sulfates by sulfotransferase from Desulfitobacterium hafniense. Journal of Molecular Catalysis B-Enzymatic, 89, 24-27. [details]
    • Wever, R., & van der Horst, M. A. (2013). The role of vanadium haloperoxidases in the formation of volatile brominated compounds and their impact on the environment. Dalton Transactions, 42(33), 11778. [details]


    • Babich, L., Hartog, A. F., van Hemert, L. J. C., Rutjes, F. P. J. T., & Wever, R. (2012). Synthesis of carbohydrates in a continuous flow reactor by immobilized phosphatase and aldolase. ChemSusChem, 5(12), 2348-2353. [details]
    • Babich, L., Hartog, A. F., van der Horst, M. A., & Wever, R. (2012). Continuous-flow reactor-based enzymatic synthesis of phosphorylated compounds on a large scale. Chemistry - A European Journal, 18(21), 6604-6609. [details]
    • But, A., Le Notre, J., Scott, E. L., Wever, R., & Sanders, J. P. M. (2012). Selective oxidative decarboxylation of amino acids to produce industrially relevant nitriles by vanadium chloroperoxidase. ChemSusChem, 5(7), 1199-1202. [details]
    • Natalio, F., Andre, R., Hartog, A. F., Stoll, B., Jochum, K. P., Wever, R., & Tremel, W. (2012). Vanadium pentoxide nanoparticles mimic vanadium haloperoxidases and thwart biofilm formation. Nature Nanotechnology, 7, 530-535. [details]
    • Persoon, I. F., Hoogenkamp, M. A., Bury, A., Wesselink, P. R., Hartog, A. F., Wever, R., & Crielaard, W. (2012). Effect of Vanadium chloroperoxidase on Enterococcus faecalis biofilms. The Journal of Endodontics, 38(1), 72-74. [details]
    • Wever, R., & van Herk, T. (2012). Hydrolysis and formation of P-O bonds. In K. Drauz, H. Gröger, & O. May (Eds.), Enzyme catalysis in organic synthesis. - 3rd ed. (pp. 1001-1033). Wiley-VCH. [details]
    • van der Horst, M. A., van Lieshout, J. F. T., Bury, A., Hartog, A. F., & Wever, R. (2012). Sulfation of various alcoholic groups by an arylsulfate sulfotransferase from Desulfitobacterium hafniense and synthesis of estradiol sulfate. Advanced Synthesis & Catalysis, 354(18), 3501-3508. Advance online publication. [details]


    • André, R., Natálio, F., Humanes, M., Leppin, J., Heinze, K., Wever, R., Schröder, H. C., Müller, W. E. G., & Tremel, W. (2011). V2O5 nanowires with an intrinsic peroxidase-like activity. Advanced Functional Materials, 21(3), 501-509. [details]
    • Babich, L., van Hemert, J. C., Bury, A., Hartog, A. F., Falcicchio, P., van der Oost, J., van Herk, T., Wever, R., & Rutjes, F. P. J. T. (2011). Synthesis of non-natural carbohydrates from glycerol and aldehydes in a one-pot four-enzyme cascade reaction. Green Chemistry, 13(10), 2895-2900. [details]
    • Hartog, A. F., van Herk, T., & Wever, R. (2011). Efficient regeneration of NADPH in a 3-enzyme cascade reaction by in situ generation of glucose 6-phosphate from glucose and pyrophosphate. Advanced Synthesis & Catalysis, 353(13), 2339-2344. [details]
    • Natalio, F., André, R., Pihan, S. A., Humanes, M., Wever, R., & Tremel, W. (2011). V(2)O(5) nanowires with an intrinsic iodination activity leading to the formation of self-assembled melanin-like biopolymers. Journal of Materials Chemistry, 21(32), 11923-11929. [details]


    • Renirie, R., Charnock, J. M., Garner, C. D., & Wever, R. (2010). Vanadium K-edge XAS studies on the native and peroxo-forms of vanadium chloroperoxidase from Curvularia inaequalis. Journal of inorganic biochemistry, 104(6), 657-664. [details]


    • Caiazzo, A., Garcia, P. M. L., Wever, R., van Hest, J. C. M., Rowan, A. E., & Reek, J. N. H. (2009). Synergy between chemo- and bio-catalysts in multi-step transformations. Organic & Biomolecular Chemistry, 7(14), 2926-2932. [details]
    • Hoogenkamp, M. A., Crielaard, W., ten Cate, J. M., Wever, R., Hartog, A. F., & Renirie, R. (2009). Antimicrobial activity of vanadium chloroperoxidase on planktonic Streptococcus mutans cells and Streptococcus mutans biofilms. Caries Research, 43(5), 334-338. [details]
    • Renirie, R., Pierlot, C., Wever, R., & Aubry, J-M. (2009). Singlet oxygenation in microemulsion catalysed by vanadium chloroperoxidase. Journal of Molecular Catalysis B-Enzymatic, 56(4), 259-264. [details]
    • van Herk, T., Hartog, A. F., Babich, L., Schoemaker, H. E., & Wever, R. (2009). Improvement of an acid phosphatase/DHAP-dependent aldolase cascade reaction by using directed evolution. ChemBioChem, 10(13), 2230-2235. [details]


    • Renirie, R., Dewilde, A., Pierlot, C., Wever, R., Hober, D., & Aubry, J-M. (2008). Bactericidal and virucidal activity of the alkalophilic P395D/L241V/T343A mutant of vanadium chloroperoxidase. Journal of Applied Microbiology, 105(1), 264-270. [details]
    • de Macedo-Ribeiro, S., Renirie, R., Wever, R., & Messerschmidt, A. (2008). Crystal structure of a trapped phosphate intermediate in vanadium apochloroperoxidase catalyzing a dephosphorylation reaction. Biochemistry, 47(3), 929-934. [details]


    • Auriol, D., ter Halle, R., Lefèvre, F., Visser, D. F., Gordon, G. E. R., Bode, M. L., Mathiba, K., Brady, D., De Winter, K., Desmet, T., Cerdobbel, A., Soetaert, W., van Herk, T., Hartog, A. F., Wever, R., Brzezińska-rodak, M., Klimek-Ochab, M., Żymańczyk-Duda, E., Mukherjee, J., ... Gruber-Khadjawi, M. (2012). Transferases for alkylation, glycosylation and phosphorylation. In J. Whittall, & P. W. Sutton (Eds.), Practical methods for biocatalysis and biotransformations (Vol. 2, pp. 231-262). Wiley. [details]
    • Kim, B. G., Ahn, J. H., Sello, G., Di Gennaro, P., van Herk, T., Hartog, A. F., Wever, R., Oroz-Guinea, I., Sánchez-Moreno, I., García-Junceda, E., Wu, B., Szymanski, W., Feringa, B. L., Janssen, D. B., Villo, L., Kreen, M., Kudryashova, M., Metsala, A., Tamp, S., ... Eddowes, P. (2012). Tandem and sequential multi-enzymatic syntheses. In J. Whittall, & P. W. Sutton (Eds.), Practical methods for biocatalysis and biotransformations (Vol. 2, pp. 313-346). Wiley. [details]
    • Wever, R. (2012). Structure and function of vanadium haloperoxidases. In H. Michibata (Ed.), Vanadium: biochemical and molecular biological approaches (pp. 95-125). Springer. [details]


    • Wever, R. (2010). Application of peroxidases. In H. B. Dunford (Ed.), Peroxidases and catalases: biochemistry, biophysics, biotechnology, and physiology (2. ed.) (pp. 403-424). Hoboken, NJ: Wiley. [details]
    • Wever, R., & Renirie, R. (2010). Structure and function of vanadium haloperoxidases. In H. B. Dunford (Ed.), Peroxidases and catalases: biochemistry, biophysics, biotechnology, and physiology (pp. 363-386). Wiley: Hoboken, NJ. [details]

    Prize / grant

    • Wever, R. (2016). Vanadis award.

    Media appearance

    Talk / presentation

    • Wever, R. (speaker) (6-11-2016). Vanadium haloperoxidases, from their discovery to their involvement in ozone breakdown in the atmosphere, International Vanadium Symposium: Chemistry, Biological Chemistry, and Toxicology, Taipei.


    • Wever, R. (participant) (6-10-2022). Enzymology -Past, Present and Future, Utrecht. Co-organizer Enzymology Symposium, “Enzymology -Past, Present and Future, Utrecht, October 6, 2022 (organising a conference, workshop, ...).
    • Wever, R. (visiting researcher) (18-1-2019). University of Copenhagen, Faculty of Science (visiting an external institution).
    This list of publications is extracted from the UvA-Current Research Information System. Questions? Ask the library or the Pure staff of your faculty / institute. Log in to Pure to edit your publications. Log in to Personal Page Publication Selection tool to manage the visibility of your publications on this list.
  • Ancillary activities
    No ancillary activities