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uva.nl
Van 't Hoff Institute for Molecular Sciences Van 't Hoff Institute for Molecular Sciences
Valorisation

Research facilities

HIMS has an extensive fleet of high quality analytical instrumentation, such as NMR, EPR, UV-Vis, HPLC and MS. HIMS offers companies - in particular small and medium enterprises (SME's) - unique access to this infrastructure, scientific software and related knowhow. HIMS scientists are always open to consider new collaborations and partnerships.

Below is a list of services we provide on regular base to third parties. More analyses can be performed upon request.

Please contact HIMS manager Marcel Bartels: M.J.Bartels@uva.nl, phone 020 525 8529. Also see our spin-off Spark904.

NMR spectrum service

  • 1D for H, C, P, F etc.
  • 2D for HSQC, NOESY etc.

NMR dedicated service

Spectrum interpretation for all nuclei measured with NMR

MS spectrum service

Accurate mass measurements for publication purposes:

  • Ionisation techniques like EI and FI coupled to GC
  • Probe available for FD and direct insertion
  • Electrospray / Coldspray

FD and Coldspray are especially suitable for instable compounds

MS-based proteomics

  • Qualitative proteomics– protein identification from gel separated or liquid samples by LC-MS/MS.
  • Quantitative targeted proteomics – using SWATH technology
  • Quantitative proteomics – using isobaric or isotopic labelling with iTRAQ and SILAC reagents.
  • Phosphorylation analysis (ID and quantitative) and other PTMs
  • Biological mass spectrometry – various analytical measurements for protein, peptide and small molecule structure determination and mass determination of proteins are offered.

Surface analysis

  • Adsorption of gasses and vapours
  • Mercury porosimetry

Vibrational Circular Dichroism spectroscopy service

  • Measurement of VCD spectra
  • Absolute configuration determination
  • Modelling services